How does electromagnetic stimulation protect myelinating brain cells?

Associate Professor Jennifer Rodger

University of Western Australia, WA

| A cure via repair and regeneration | Neurobiology | Incubator | 2023 | Investigator Led Research |
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Summary

In people with MS, high levels of inflammation are thought to cause the death of myelin-producing cells in the brain called oligodendrocytes, leading to a loss of brain function. Associate Professor Jennifer Rodger’s team recently showed that a non-invasive technique called repetitive transcranial magnetic stimulation (rTMS) can improve the survival of oligodendrocytes. However, the brain is a very complex organ which contains many different types of cells that work together.  

Associate Professor Rodger’s team aims to find the parts of cells that are targeted by rTMS so that future experiments can identify the factors that are responsible for oligodendrocyte survival. Understanding these targets may lead to treatments that maximise the survival of these special brain cells, thereby to preserving brain function in people with MS. 

Updated 31 March 2024 

Updated: 22 February, 2023

Stages of the research process

Fundamental laboratory
Research

Laboratory research that investigates scientific theories behind the possible causes, disease progression, ways to diagnose and better treat MS.

Lab to clinic timeline: 10+ years
Translational
Research

Research that builds on fundamental scientific research to develop new therapies, medical procedures or diagnostics and advances it closer to the clinic.

Lab to clinic timeline: 5+ years
Clinical Studies
and Clinical Trials

Clinical research is the culmination of fundamental and translational research turning those research discoveries into treatments and interventions for people with MS.

Lab to clinic timeline: 1-5 years

Co-investigator

Total Funding

  • $25,000

Duration

  • 2 years – starting 2023

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Ms Alice Saul

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How does electromagnetic stimulation protect myelinating brain cells?